Science

13 January 2008

Will sleep be soon a thing of the past?

From WIRED.COM, they report about the possibility of replacing sleep by snorting a chemical.

In what sounds like a dream for millions of tired coffee drinkers, Darpa-funded scientists might have found a drug that will eliminate sleepiness.

A nasal spray containing a naturally occurring brain hormone called orexin A reversed the effects of sleep deprivation in monkeys, allowing them to perform like well-rested monkeys on cognitive tests. The discovery's first application will probably be in treatment of the severe sleep disorder narcolepsy.

The treatment is "a totally new route for increasing arousal, and the new study shows it to be relatively benign," said Jerome Siegel, a professor of psychiatry at UCLA and a co-author of the paper. "It reduces sleepiness without causing edginess."

Orexin A is a promising candidate to become a "sleep replacement" drug. For decades, stimulants have been used to combat sleepiness, but they can be addictive and often have side effects, including raising blood pressure or causing mood swings. The military, for example, administers amphetamines to pilots flying long distances, and has funded research into new drugs like the stimulant modafinil and orexin A in an effort to help troops stay awake with the fewest side effects.

What do have to say about this?  Give me one of those, please!  Soon!

Well as long as there are no side-effects, I'm in.

24 September 2007

The Irrationality of the Human Mind

A lot of disciplines think of the human mind as a rational creature. That the human being is rational at her core.  But are we, really?

The irrationality of the human mind is interesting: it contorts our views and our human behavior models. It distorts schemas and other things that we have in our minds of human behavior.  Yet this irrationality is also that which is perhaps at the cornerstone of our being human.

The complexity of our being human is perhaps found in our seeming irrationality.  How and why we believe in a God and in religion, in ideals that are nonetheless beyond logic and science, in goals that are beyond reason.

We try to distill this complexity by assuming rationality - an assumption that is easily questioned by the things that we observe in our daily lives. 

A good friend - on Saturday night, however, asked me via email:  Could it be that underneath our seeming irrationality is a 'pure rationality' that unfortunately, we cannot define at the moment?  Could it be that underneath the seeming drives of fulfilling desires and pleasures - which is sometimes assumed as part of the rationality of humans - is more than just that?  Could it be possible that even in the "evil of greed" lies a kernel of good - and in the "altruism" of humans lies a kernel of evil?

I have no answer.

I can only try to be rational - but in so doing, be irrational.

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